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The four-star Hotel Amadeus is no more than five minutes from Venice's main railway station, on the main pedestrian street that leads toward the Piazza San Marco.
When you reach the wide fondamenta or pavement in front of the station, turn left.
Walk past the Scalzi Church and the Scalzi Bridge toward the Rio Terà Lista di Spagna (a busy pedestrian thoroughfare).
Continue down the Lista di Spagna for two or three minutes. You'll see the Hotel Amadeus on your left, in a large yellow building with flags on the façade.
Look for the Calatrava Bridge (a.k.a. the Ponte della Costituzione). It's the large modern bridge at the northeast corner of the square, next to the Hotel Santa Chiara.
Cross the bridge and continue straight ahead, past the large building on your left, to the train station.
From the station, follow the directions above.
Take a shuttle bus, a taxi, or the People Mover to the Piazzale Roma.
Follow the directions above.
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